HCID 53805673, compound → HCID 86755541, compound

HRID 2289111Notes

Reaction equation

HRID 2289111 reaction equation
[C:1]([O:4][C:5]1[CH:10]=[C:9]([O:11][CH3:12])[C:8]([OH:13])=[C:7]([O:14][CH3:15])[C:6]=1[CH3:16])(=[O:3])[CH3:2].Br[CH2:18][CH2:19][CH2:20][O:21][C:22]1[CH:23]=[CH:24][C:25]2[C:26]([CH2:34][CH3:35])=[N:27][O:28][C:29]=2[C:30]=1[CH2:31][CH2:32][CH3:33]>>[C:1]([O:4][C:5]1[CH:10]=[C:9]([O:11][CH3:12])[C:8]([O:13][CH2:18][CH2:19][CH2:20][O:21][C:22]2[CH:23]=[CH:24][C:25]3[C:26]([CH2:34][CH3:35])=[N:27][O:28][C:29]=3[C:30]=2[CH2:31][CH2:32][CH3:33])=[C:7]([O:14][CH3:15])[C:6]=1[CH3:16])(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 53805673HCID 53805673, compoundHCID 69968236HCID 69968236, compound

Product 1

HCID 86755541HCID 86755541, compoundYield 39.1%

Procedure

The procedure from Example 76 Step C was followed using methyl-3,5-dimethoxy-4-hydroxyphenyl acetate (108 mg) and 3-bromo-1-(3-(Ethyl)-7-(propyl)-6-benz-[4,5]-isoxazoloxy)propane (156 mg) to afford a colorless oil (88 mg). NMR (CDCl3); δ 7.41 (d,2H), 6.99 (d,2H), 6.45 (s,2H), 3.76 (s,6H), 3.71 (s,3H), 3.55 (s,3H), 1.43 (t,3H), 0.92 (t,3H).

Sources & evidence

ORD record
ord-1c79143f475b4446b9a384121f0d7aec
Source dataset
uspto-grants-2000_07
Patent number
US06090836

Reaction notes

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