HCID 18701920, compound → HCID 70253217, compound

HRID 2289126Notes

Reaction equation

HRID 2289126 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH2:13][C:14]([O:16][CH3:17])=[O:15])[CH:5]=[CH:6][C:7]=1[NH:8][CH2:9][CH2:10][CH2:11]Br.[F:18][C:19]([F:34])([F:33])[C:20]1[C:24]2[CH:25]=[CH:26][C:27]([OH:32])=[C:28]([CH2:29][CH2:30][CH3:31])[C:23]=2[O:22][N:21]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([CH2:13][C:14]([O:16][CH3:17])=[O:15])[CH:5]=[CH:6][C:7]=1[NH:8][CH2:9][CH2:10][CH2:11][O:32][C:27]1[CH:26]=[CH:25][C:24]2[C:20]([C:19]([F:34])([F:33])[F:18])=[N:21][O:22][C:23]=2[C:28]=1[CH2:29][CH2:30][CH3:31]

Participants

3

Reactant 2

HCID 18701920HCID 18701920, compoundHCID 1358008127-Propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-ol

Product 1

HCID 70253217HCID 70253217, compound

Procedure

Using the method in example 17 step D substituting Methyl 3-chloro-4-(3-bromopropylamino)phenylacetate and 3-trifluoromethyl-7-propyl-6-hydroxybenz-[4,5]-isoxazole as the starting materials, the titled compound was obtained.

Sources & evidence

ORD record
ord-b67018caa6ec414c868a62073f59790d
Source dataset
uspto-grants-2000_07
Patent number
US06090836

Reaction notes

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