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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2289174Generated: October 30, 2026

Ethyl 4-oxocyclohexanecarboxylate → Rac-(1s,4s)-4-(hydroxymethyl)cyclohexanol

https://huagongshe.com/reaction/2289174

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 4-oxocyclohexanecarboxylateHCID 317638—
ReactantAluminium lithium hydrideHCID 21226445—
SolventTetrahydrofuranHCID 8028—
ProductRac-(1s,4s)-4-(hydroxymethyl)cyclohexanolHCID 12892866—

Reaction Steps

Ethyl 4-oxocyclohexanecarboxylate (Aldrich Chemical Co., Milwaukee, Wis.) is reduced with excess lithium aluminum hydride in tetrahydrofuran to provide 4-(hydroxymethyl)cylohexan-1-ol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06090950
Source datasetuspto-grants-2000_07
ORD IDord-0f9239c37cbc4506a28348a60dc29198
Source noteuspto-grants-2000_07