Cornforth reagent → HCID 22633626, compound

HRID 2289176Notes

Reaction equation

HRID 2289176 reaction equation
[C:1]([O:4][CH2:5][CH:6]1[CH2:11][CH2:10][CH:9]([OH:12])[CH2:8][CH2:7]1)(=[O:3])[CH3:2].[Cr](O[Cr]([O-])(=O)=O)([O-])(=O)=O.[NH+]1C=CC=CC=1.[NH+]1C=CC=CC=1>C(Cl)Cl>[C:1]([O:4][CH2:5][CH:6]1[CH2:11][CH2:10][C:9](=[O:12])[CH2:8][CH2:7]1)(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 2724130Cornforth reagentHCID 69317115HCID 69317115, compound

Product 1

HCID 22633626HCID 22633626, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The 4-(acetoxymethyl)cylohexan-1-ol obtained above is oxidized with 3.0 equivalents of pyridinium dichromate in refluxing methylene chloride to afford 4-(acetoxymethyl)cyclohexan-1-one.

Sources & evidence

ORD record
ord-be706c6a2b6b443b9ee7fb950b0d7cec
Source dataset
uspto-grants-2000_07
Patent number
US06090950

Reaction notes

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