Acetonitrile → HCID 15896058, compound

HRID 2289591Notes

Reaction equation

HRID 2289591 reaction equation
C([N:5]1[C:12](=O)[N:11]2[C:7](=[N:8][C:9]3[CH:17]=[CH:16][CH:15]=[CH:14][C:10]=32)[S:6]1)CCC.[C:18](#N)C>>[CH3:18][C:12]1[N:11]2[C:7](=[N:8][C:9]3[CH:17]=[CH:16][CH:15]=[CH:14][C:10]=32)[S:6][N:5]=1

Participants

3

Reactant 2

HCID 6342AcetonitrileHCID 13034031HCID 13034031, compound

Product 1

HCID 15896058HCID 15896058, compoundYield 88%

Procedure

2-Butyl-1,2,4-thiadiazolo[4,5-a]benzimidazole-3(2H)-one (1.00 g, 4.04 mmol) was refluxed in 100 mL acetonitrile for 18 h. The solvent was then evaporated and the residue was recrystallized from methanol to give 0.671 g (88%) of the title compound: mp 192-193° C.; 1H NMR (CDCl3) δ 7.81 (dm, 2H), 7.47 (td, 1H), 7.34 (td, 1H), 2.92 (s, 3H) ppm; IR (KBr) ν 1564, 1481, 1453, 1430, 1304, 1208, 756, 745 cm-1 ; MS m/z 189 (M+), 148 (M+ --CH3CN)

Workup

  1. customThe solvent was then evaporated
  2. customthe residue was recrystallized from methanol

Sources & evidence

ORD record
ord-bd2fa91afea44a17b9490d1b58b17512
Source dataset
uspto-grants-2000_07
Patent number
US06093738

Reaction notes

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