Monobenzone → HCID 101742540, compound

Participants

Reaction Steps

A suspension of 20.00 g (5.74×10-2 mol) of hexachlorocyclotriphosphazene, 22.99 g (0.57 mol) of NaH 60% oil dispersion, and 1.5 g of tetrabutylammonium bromide in 200 mL of THF is treated with 115.1 g (0.57 mol) of 4-(benzyloxy)phenol in 250 mL of THF. This treatment is performed dropwise, waiting each time for hydrogen evolution. The reaction mixture is successively refluxed for 48 hrs, cooled to room temperature, and ultracentrifuged at 8000 rpm to separate the liquid from the solid. The liquor is evaporated to dryness with a rotovap. The solid brown paste obtained is treated successively with methanol to obtain a white powder which is isolated by filtration, thoroughly washed with water and methanol, and dried. The resulting Hexakis(4-benzyloxyphenoxy)cyclotriphosphazene trimer is purified by multiple crystallizations from 50% THF/CH3OH mixtures.

Provenance & Evidence