4-Chlorobenzylamine → HCID 178522857, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 0.50 g of ethyl 4-hydroxy-3-quinolinecarboxylate (J. Amer. Chem. Soc., 68, 1264 (1946)) and 5.0 mL of 4-chlorobenzylamine is stirred 18 h at 200° C. The mixture is cooled to 25° C. and it is diluted with 25 mL of hexanes. After stirring for an additional 1 h the solid precipitate is collected by filtration and washed with 10 mL of hexanes. It is dried at 20 torr and 45° C. for 18 h. The yield is 0.28 g.

Provenance & Evidence