4-Chlorobenzylamine → HCID 178522891, compound

Participants

Reaction Steps

Ethyl 8-chloro-4-hydroxyquinoline-3-carboxylate (1.21 g) and 4-chlorobenzyl-amine (1.8 mL) are heated at 180° C. for 2 hours. The reaction is cooled to room temperature and the resulting solid filtered, washed thoroughly with diethyl ether and methylene chloride, and dried to give the desired product (1.44 g).

Provenance & Evidence