HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propargyl alcohol → HCID 178522867, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propargyl alcohol | HCID 7859 | — |
| Reactant | HCID 178522889 | HCID 178522889 | — |
| Catalyst | Copper iodide | HCID 83717 | — |
| Catalyst | HCID 178418476 | HCID 178418476 | — |
| Solvent | Diethylamine | HCID 8021 | — |
| Product | HCID 178522867 | HCID 178522867 | — |
Reaction Steps
To a mixture of the title compound of Example 39 (0.439 g), copper iodide (0.010 g) and dichlorobis(triphenylphosphine)palladium (II) (0.035 g) in 15 mL diethylamine is added propargyl alcohol (0.058 mL). The reaction is allowed to stir overnight. The solvents are evaporated and the residue is chromatographed on silica, eluting with 3% MeOH/CH2Cl2 to yield 0.271 g of the desired product as a tan solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06093732 |
| Source dataset | uspto-grants-2000_07 |
| ORD ID | ord-d0991543aae94a9499ff4b6f6b4cf1ce |
| Source note | uspto-grants-2000_07 |