3-Nitrophenylboronic Acid → HCID 23433535, compound

Participants

Reaction Steps

This compound was prepared by General Method 14 (EXAMPLE 191) from 3-nitrobenzeneboronic acid (0.47 g, 2.8 mmol), 4-bromo-2-ethylaniline (432 mg, 2.16 mmol), and (PPh3)4Pd (75 mg, 0.065 mmol) to afford 139 mg (20%) of 4-amino-3-ethyl-3'-nitrobiphenyl. Data for 4-amino-3-ethyl-3'-nitrophenyl: 1H NMR (400 MHz, acetone-d6) 8.38 (t, J=2.1, 1 H), 8.08 (m, 1 H), 8.00 (m, 1 H), 7.66 (t, J=8.0, 1 H), 7.45 (d, J=2.3, 1 H), 7.39 (dd, J=8.3, 2.3, 1 H), 6.83 (d, J=8.3, 1 H), 4.68 (br s, 2 H).

Provenance & Evidence