Potassium Hydroxide → HCID 9927310, compound

Participants

Reaction Steps

Following general procedure G and using 4-[ethyl-(3,3,7-trimethyl-2,3-dihydro-benzofuran-5-yl)-amino]-benzoic acid ethyl ester (Compound 20, 0.013 g, 0.37 mmol) and 1 mL (4 mmol) of 4M potassium hydroxide solution in 1.1 mL of ethanol, the title compound (0.009 g, 75%) was obtained as a solid. 1H NMR (300 MHz, CDCl3): δ 7.86 (d, 2H, J=9.0 Hz), 6.77 (s, 1H), 6.75 (s, 1H), 6.57 (d, 2H, J=9.0 Hz), 4.29 (s, 2H), 3.72 (q, 2H, J=7.1 Hz), 2.21 (s, 3H), 1.33 (s, 6H), 1.25 (t, 3H, J=7.1 Hz).

Provenance & Evidence