9-Iodo-9-borabicyclo(3.3.1)nonane → 7-Isopropyl-5-[isopropyl-(4-hydroxy-phenyl)-amino]-3,3,6-trimethyl-2,3-dihydro-benzofuran

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Reaction Steps

Following general procedure M and using 7-isopropyl-5-[isopropyl-(4-methoxy-phenyl)-amino]-3,3,6-trimethyl-2,3-dihydro-benzofuran (Compound 55, 0.077 g, 0.21 mmol) and 1M solution of 9-iodo-9-borabicyclo[3.3.1]nonane (B-iodo-9-BBN) in hexanes (0.25 mL, 0.25 mmol) in 2 mL of anhydrous dichloromethane, the title compound (0.06 g, 77%) was obtained as a brown oil that was used in the next step without further purification.

Provenance & Evidence