Allyl Isothiocyanate → HCID 20231874, compound

Participants

Reaction Conditions

Reaction Steps

Into a stirred mixture of 20 g (0.2 mole) methyl hydrazinocarboxylate in 150 ml methylene chloride, 19.8 g (0.2 mole) allyl isothiocyanate in 50 ml methylene chloride was dropped in. The reaction mixture was refluxed at about 40° C. for 3.5 hours, allowed to stir overnight at ambient temperature, refluxed about 8 hours, stirred overnight at ambient temperature, refluxed 8 hours, stirred overnight at ambient temperature, and refluxed an additional 4 hours. The reaction mixture was cooled, vacuum filtered and the solids dried. The filtrate was poured back into the flask, at which point a precipitate started to form. Hexane was added. A yellow precipitate formed which was vacuum filtered and dried to give 29.6 g of the above-identified product.

Provenance & Evidence