Ethanol → HCID 131714931, compound

Participants

Reaction Steps

6-chloropurineriboside (5.8 g, 20 mmol, 2,3-propylaminediol (1.82 g, 20 mmol) and triethylamine (2.02 g, 20 mmol) were combined in 250 ml ethanol and refluxed for 18 hours. Removal of the ethanol gave a viscous syrup. Refluxing ethanol was added to the syrup sufficient to dissolve it, then allowed to cool and stand at 0° for 24 hours. The resulting crystals were filtered and dried, yielding 3.6 g (53%) m.p. 164°-165° analysis for C13H19N5O6) Calcd: C=45.74, H=5.61, N=20.52; Found: C=45.93, H=5.49, N=20.63, H2O 0.70.

Provenance & Evidence