反应详情

3.65 g (23.5 mmoles) of cyanimino-dithiocarbonic acid dimethylester (purity: 94%) and 5.43 g (30 mmoles) of N-(4-methylbenzyl)-cysteamine are boiled in 30 ml of ethanol until the evolution of methyl-mercaptan terminates (about 2 hours). The reaction mixture is evaporated and the crystalline residue is recrystallized from 6 ml of isopropanol. 4.65 g (85.5%) of 2-cyanimino-N-(4-methylbenzyl)-thiazolidine are obtained, melting at 102° to 104° C.

1. customThe reaction mixture is evaporated
2. customthe crystalline residue is recrystallized from 6 ml of isopropanol