反应详情

A solution of 0.30 gram (0.0078 mole) of sodium borohydride in 5 milliliters of water was added to a solution of 0.75 gram (3.2 millimoles) of 3-chloro-5H-dibenzo[a,d]cyclohepten-5-one in 50 milliliters of methanol and the resulting mixture heated for 15 minutes at reflux temperature to obtain 3-chloro-5H-dibenzo[a,d]cyclohepten-5-ol intermediate in the reaction mixture. The solvent was evaporated and the residue intermediate slurried with water, filtered, washed and dried at 65° C. in vacuum oven for three hours.

1. temperaturethe resulting mixture heated for 15 minutes
2. temperatureat reflux temperature