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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2290309Generated: October 31, 2026

Ethanol → Indoline-2-carboxylic acid

https://huagongshe.com/reaction/2290309

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
ReactantIndolineHCID 10328—
ReactantSodium HydroxideHCID 14798—
ProductIndoline-2-carboxylic acidHCID 86074—

Reaction Steps

31.5 g of the above indoline (86%) are obtained by saponification in 250 ml of normal sodium hydroxide solution and 150 ml of ethanol for 8 hours at room temperature of 43 g (0.224 mol) of the corresponding ethyl ester prepared according to E. J. COREY et al. (J. Amer. Chem. Soc. 1970 92, p. 2476).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04616030
Source datasetuspto-grants-1986_10
ORD IDord-8493b01642ea47eda51abe0264b21a75
Source noteuspto-grants-1986_10