Ethyl Acetate → HCID 15586353, compound

Participants

Reaction Steps

Sodium borohydride (3.4 g) was added portionwise to a stirred solution of 5-methyl-3-methylthio-6-phenyl-1,2,4-triazine (10 g) in tetrahydrofuran (25 ml). To the reaction mixture was added ethyl acetate, and the mixture was washed successively with 1N-hydrochloric acid, water and brine, dried over sodium sulfate, and concentrated to dryness. The residual solid was recrystallized from a mixture of ethanol and water to give 5-methyl-3-methylthio-6-phenyl-2,5-dihydro-1,2,4-triazine (3.46 g), m.p. 159°~160° C.

Provenance & Evidence