Diisopropyl Ether → HCID 20232041, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 3-hydrazino-5-hydrazino-5-methyl-6-phenyl-1,2,4-triazine (6.6 g), triethylamine (5.4 g), 2-t-butoxycarbonyloxyimino-2-phenylacetonitrile (9.76 g) in tetrahydrofuran (60 ml) was heated at 63° C. for 5.5 hours with stirring and then allowed to stand at room temperature for 61 hours. The mixture was treated with diisopropyl ether (40 ml), and the resultant precipitates were collected by filtration, washed successively with diisopropyl ether, methanol and diisopropyl ether, and dried to give 3-(2-t-butoxycarbonylhydrazino)-5-methyl-6-phenyl-1,2,4-triazine (8.92 g).

Provenance & Evidence