HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propylene Oxide → Methyl 4-[1-(2-hydroxypropyl)-piperazin-4-ylmethyl]-benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propylene Oxide | HCID 6378 | — |
| Reactant | Methyl 4-[(piperazin-1-yl)methyl]benzoate | HCID 7018627 | — |
| Product | Methyl 4-[1-(2-hydroxypropyl)-piperazin-4-ylmethyl]-benzoate | HCID 54404285 | 63% |
Reaction Steps
This is prepared analogously to Example 11 from methyl 4-(piperazin-1-ylmethyl)-benzoate and propylene oxide. Yield 63% of theory; m.p. 63°-64° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04616086 |
| Source dataset | uspto-grants-1986_10 |
| ORD ID | ord-104689d171e04e2fb64f2830cf80e88e |
| Source note | uspto-grants-1986_10 |