HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus trichloride → HCID 20232478, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus trichloride | HCID 24387 | — |
| Reactant | 3-(3',5'-Di-tert-butyl-4'-hydroxyphenyl)propionic acid | HCID 88389 | — |
| Reactant | Ethyl 4-[2-(1-piperazinyl)ethyl]benzoate | HCID 20232457 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 20232478 | HCID 20232478 | 62% |
Reaction Steps
This is prepared analogously to Example 12 from ethyl 4-[2-(piperazin-1-yl)-ethyl]-benzoate, 3-(3,5-di-tert.-butyl-4-hydroxyphenyl)-propionic acid, phosphorus trichloride and pyridine. Yield 62% of theory; m.p. 105°-107° C. (recrystallised from ethyl acetate/ligroin).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04616086 |
| Source dataset | uspto-grants-1986_10 |
| ORD ID | ord-bc19979a8f05415e83d41b235afab659 |
| Source note | uspto-grants-1986_10 |