Propylene Oxide → HCID 20232425, compound

HRID 2290468Notes

Reaction equation

HRID 2290468 reaction equation
[N:1]1([CH2:7][CH2:8][C:9]2[CH:14]=[CH:13][C:12]([CH2:15][C:16]([O:18][CH2:19][CH3:20])=[O:17])=[CH:11][CH:10]=2)[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[CH2:21]1[O:24][CH:22]1[CH3:23]>>[OH:24][CH:22]([CH3:23])[CH2:21][N:4]1[CH2:5][CH2:6][N:1]([CH2:7][CH2:8][C:9]2[CH:14]=[CH:13][C:12]([CH2:15][C:16]([O:18][CH2:19][CH3:20])=[O:17])=[CH:11][CH:10]=2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 6378Propylene OxideHCID 20232558HCID 20232558, compound

Product 1

HCID 20232425HCID 20232425, compoundYield 92%

Procedure

This is prepared analogously to Example 11 by the reaction of ethyl 4-[2-(piperazin-1-yl)-ethyl]-phenylacetate with propylene oxide. Yield 92% of theory; colourless oil.

Sources & evidence

ORD record
ord-220a10549c53495b86afaee46edbb958
Source dataset
uspto-grants-1986_10
Patent number
US04616086

Reaction notes

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