2,5-Dimethoxytetrahydrofuran → HCID 7303337, compound

HRID 2290554Notes

Reaction equation

HRID 2290554 reaction equation
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([NH2:11])=[C:8]([OH:10])[CH:9]=1)([O-:3])=[O:2].CO[CH:14]1[CH2:18][CH2:17][CH:16](OC)O1>C(O)(=O)C>[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([N:11]2[CH:14]=[CH:18][CH:17]=[CH:16]2)=[C:8]([OH:10])[CH:9]=1)([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 790982,5-DimethoxytetrahydrofuranHCID 49847212-Amino-5-Nitrophenol

Product 1

HCID 7303337HCID 7303337, compoundYield 44.9%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

In a manner similar to Example 1, Step A, the reaction of 10.0 g (0.06 mole) of 5-nitro-2-aminophenol with 9.8 g (0.07 mole) of 2,5-dimethoxytetrahydrofuran in 20 ml of glacial acetic acid produced 5.5 g of 5-nitro-2-(1H-pyrrol-1-yl)phenol.

Sources & evidence

ORD record
ord-3489bc76b29949178cdc8eef5f8b34f4
Source dataset
uspto-grants-1986_10
Patent number
US04617316

Reaction notes

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