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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2290566Generated: November 1, 2026

1-(p-cyanophenylmethyl)-5-(2-formylethyl)-1H-imidazole → 5-(p-Cyanophenyl)-7,8-dihydroimidazo[1,5-a]pyridine

https://huagongshe.com/reaction/2290566

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(p-cyanophenylmethyl)-5-(2-formylethyl)-1H-imidazoleHCID 15294731—
ReactantPotassium tert-butoxideHCID 23665647—
SolventEthanolHCID 702—
Product5-(p-Cyanophenyl)-7,8-dihydroimidazo[1,5-a]pyridineHCID 15294718—

Reaction Steps

A solution of 0.24 g of 1-p-cyanophenylmethyl-5-(2-formylethy)-1H-imidazole in 10 ml of anhydrous ethanol is refluxed under nitrogen for 2 hours with 20 mg of potassium tert-butoxide, cooled and evaporated to yield the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04617307
Source datasetuspto-grants-1986_10
ORD IDord-b142a42806524519aebbed88ae9cb373
Source noteuspto-grants-1986_10