HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-2-methylaniline → Quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-2-methylaniline | HCID 6894 | — |
| Reactant | 1-Penten-3-one | HCID 15394 | — |
| Reactant | 7-Chloro-3-ethyl-1,2,3,4-tetrahydro-8-methylquinoline | HCID 20231581 | — |
| Reactant | HCID 20231582 | HCID 20231582 | — |
| Product | Quinoline | HCID 7047 | 60% |
Reaction Steps
The procedure described in Example 1 was followed, except that 187 g/hour of ethylacrolein and 283 g/hour of 3-chloro-2-methylaniline were employed. Distillation gave 335 g of distillate at a boiling point of 125° C./2 mm Hg. This distillate contained 75% by weight of 3-ethyl-7-chloro-8-methylquinoline and 22% by weight of 3-ethyl-7-chloro-8-methyltetrahydroquinoline, corresponding to a quinoline yield of 60%, based on 3-chloro-2-methylaniline employed.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04617395 |
| Source dataset | uspto-grants-1986_10 |
| ORD ID | ord-8b63cdd7c5674eae8cf7d3b1873c5730 |
| Source note | uspto-grants-1986_10 |