Triphenylphosphine → HCID 20231593, compound

Participants

Reaction Steps

p-Nitrobenzylbromide (54.0 g, 0.25 mol) and triphenylphosphine (65.6 g, 0.25 mol) were dissolved in 150 mL of dry benzene in a flask equipped with a drying tube. The solution was heated on a steam bath with swirling until a majority of product had precipitated (5 min), and then was allowed to cool to near ambient temperature with occasional agitation. Filtration of the precipitate and washing with 3×200 mL anhydrous ether yielded 100.8 g of the desired product as an off-white powder. The filtrate was flash evaporated to 50 mL and heated on a steam bath for 5 min, then chilled overnight to provide an additional 11.4 g of product (93.8% yield).

Provenance & Evidence