Ammonia → HCID 68830865, compound

Participants

Reaction Conditions

Reaction Steps

(4,5-Dimethylfuran-2-yl)-(4-methylpyridin-3-yl)-methanone (150 mg), methanol (2 ml), and a 28% aqueous ammonia solution (2 ml) were placed in a sealed tube and was stirred at 160° C. overnight. The reaction solution was cooled to room temperature, and the solvent was then removed by distillation under the reduced pressure, and the residue was purified by thin layer chromatography using hexane-acetone to give 5,6,4′-trimethyl-[2,3′]bipyridin-3-ol (30 mg, yield 20%).

Provenance & Evidence