Sodium Hydroxide → HCID 20231627, compound

Participants

Reaction Steps

The compound of Example 6 (600 mg, 1.51 mmoles) was taken up in THF (5 ml) to which was added 1N NaOH (4 ml). The reaction mixture was stirred at room temperature. The THF was removed in vacuo and the residue was diluted with H2O and extracted with CHCl3. The aqueous phase was acidified with conc. HCl and extracted with CHCl3. The organic extract was dried and concentrated in vacuo. The title compound was crystallized from ether/hexane.

Provenance & Evidence