Methanesulfonyl chloride → HCID 20231630, compound

Participants

Reaction Steps

The compound of Example 8 (250 mg) was dissolved in dry pyridine (5 ml) and cooled to 0°. Methanesulfonylchloride (100 μl) was added to the stirred solution, which warmed to room temperature and stirred for 16 hours. The pyridine was removed in vacuo and the residue was partitioned between ethyl acetate and water. The organic phase was washed with dilute acid, water, dried and evaporated to afford the title compound, m.p. 158°-162°.

Provenance & Evidence