Sodium Acetate → HCID 178449934, compound

HRID 2290676Notes

Reaction equation

HRID 2290676 reaction equation
C([O-])(=O)C.[Na+].[Cl-].[CH2:7]([O:9][NH3+:10])[CH3:8].[C:11]([CH:16]1[C:21](=[O:22])[CH2:20][CH:19]([CH:23]2[CH:28]([CH3:29])[CH2:27][CH2:26][O:25][CH2:24]2)[CH2:18][C:17]1=[O:30])(=O)[CH2:12][CH2:13][CH3:14]>C(O)C>[CH2:7]([O:9][NH:10][C:11](=[C:16]1[C:17](=[O:30])[CH2:18][CH:19]([CH:23]2[CH:28]([CH3:29])[CH2:27][CH2:26][O:25][CH2:24]2)[CH2:20][C:21]1=[O:22])[CH2:12][CH2:13][CH3:14])[CH3:8]

Participants

5

Reactant 3

HCID 517045Sodium AcetateHCID 19001768HCID 19001768, compoundHCID 20229925HCID 20229925, compound

Product 1

HCID 178449934HCID 178449934, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

3.69 parts by weight of sodium acetate and 3.51 parts by weight of ethoxyammonium chloride were added to 10.0 parts by weight of 2-butyryl-5-(4-methyltetrahydropyran-3-yl)-cyclohexane-1,3-dione in 100 ml of ethanol, and the mixture was stirred for 20 hours at room temperature. To work up the mixture, it was poured into ice water and extracted with methylene chloride, and the organic phase was washed with water, dried and evaporated down to give 10.7 parts by weight of 2-(1-ethoxyaminobutylidene)-5-(4-methyltetrahydropyran-3-yl)-cyclohexane-1,3-dione (active ingredient No. 1); nD22 =1.5235.

Workup

  1. extractionextracted with methylene chloride
  2. washthe organic phase was washed with water
  3. customdried
  4. customevaporated down

Sources & evidence

ORD record
ord-abb2670990a145c59f8ce5507f239216
Source dataset
uspto-grants-1986_10
Patent number
US04618362

Reaction notes

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