Hydrochloric Acid → HCID 53672780, compound

Participants

Reaction Steps

To a mixture obtained by adding 0.1 g of lithium aluminum hydride to 20 ml of ether was added 0.55 g of 1-(3,4-dibenzyloxyphenyl)-1-octen-3-one under ice-cooling and the mixture was stirred for one hour at room temperature. To the reaction mixture was gradually added 10 ml of an aqueous 10% hydrochloric acid solution and the ether layer was collected, washed with water, and concentrated under reduced pressure to provide a solid product. By washing the product with a mixture of ether and n-hexane (1:3), 0.4 g of 1-(3,4-dibenzyloxyphenyl)-4-methyl-1-octen-3-ol was obtained.

Provenance & Evidence