HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trichloroacetic Acid → 97139-60-1
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trichloroacetic Acid | HCID 6421 | — |
| Reactant | 4-Hydroxycyclophosphamide | HCID 99735 | — |
| Reactant | HCID 53692199 | HCID 53692199 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 97139-60-1 | HCID 13770902 | — |
Reaction Steps
560 mg (2 mmol) of 4-hydroxycyclophosphamide in 10 ml of acetone were treated with 460 mg of 3-o-bromophenyl-1-hydroxyurea and a catalytic amount of trichloroacetic acid and let to stand at -25° C. After 2 days, the crystals were drawn off by suction and recrystallized from acetone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04618692 |
| Source dataset | uspto-grants-1986_10 |
| ORD ID | ord-322d5294f3384fc2b187c9c338787c3f |
| Source note | uspto-grants-1986_10 |