HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 178418552, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Fluorophenyl isocyanate | HCID 70955 | — |
| Reactant | 3-[4-(4-Chlorobenzyl)piperazin-1-yl]propanethiol dihydrochloride | HCID 13731118 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178418552 | HCID 178418552 | 92.3% |
Reaction Steps
The procedure described in Example 2 was followed, using 0.8 g of 4-fluorophenyl isocyanate, 2.2 g of 3-[4-(4-chlorobenzyl)piperazin-1-yl]propanethiol dihydrochloride, 0.6 g of triethylamine and 25 ml of methylene chloride, to give 1.41 g (47% of theory) of N-(4-fluorophenyl)-S-{3-[4-(4-chlorobenzyl)piperazin-1-yl]propyl}thiocarbamate dihydrochloride as a white crystalline solid, M.p. 250°-252° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04618677 |
| Source dataset | uspto-grants-1986_10 |
| ORD ID | ord-6b9bc908a5f044ff84d89f6927a8efb0 |
| Source note | uspto-grants-1986_10 |