HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenyl isocyanate → HCID 178418520, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenyl isocyanate | HCID 7672 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 3-[4-(1-Phenylethyl)piperazin-1-yl]propanethiol dihydrochloride | HCID 13731122 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178418520 | HCID 178418520 | 94.8% |
Reaction Steps
The procedure described in Example 2 was followed, using 1.6 g of phenyl isocyanate, 4.5 g of 3-[4-(1-phenylethyl)piperazin-1-yl]propanethiol dihydrochloride, 1.3 g of triethylamine and 50 ml of methylene chloride, to give 2.1 g (38% of theory) of N-phenyl-S-{3-[4-(1-phenylethyl)piperazin-1-yl]propyl}thiocarbamate dihydrochoride dihydrate as a white crystalline solid, M.p. 227°-229° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04618677 |
| Source dataset | uspto-grants-1986_10 |
| ORD ID | ord-7c42b30d0b2448ff8a7157b6ad1f31cf |
| Source note | uspto-grants-1986_10 |