HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Alanine → (S)-2-(phenylsulfonamido)propanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Alanine | HCID 5950 | — |
| Reactant | Benzenesulfonyl chloride | HCID 7369 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | (S)-2-(phenylsulfonamido)propanoic acid | HCID 7114743 | 95% |
Reaction Steps
N-benzenesulfonylalanine was prepared by mixing equimolar quantities of alanine and benzenesulfonyl chloride at 60° C. in aqueous sodium hydroxide (200 mol%). A 95% yield was obtained. The method is set out in the previously mentioned book "Chemistry Of The Amino Acids".
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04618710 |
| Source dataset | uspto-grants-1986_10 |
| ORD ID | ord-426399edc266420e8327c4a0943796f2 |
| Source note | uspto-grants-1986_10 |