Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethylamine | HCID 6341 | — |
| Reactant | FSCZNKNUJVBMPY-UHFFFAOYSA-N | HCID 13242777 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 20142134 | HCID 20142134 | — |
Reaction Steps
4 g (13 mmoles) of N-(2-benzyl propenoyl)-glycine p.fluorobenzyl ester, 14, are dissolved in 15 ml of pyridine. 1.02 g (13 mmoles) of ethylamine in solution in the pyridine are added. The solution is heated to 120° C. for 2 hours. At the end of the reaction, the solution is concentrated to 5 ml, and 50 ml of ether are added. A white product precipitates. It is filtered, washed with water, and then with ether. It is recrystallized in a 50/50 CH3OH/H2O mixture. White crystals are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04618708 |
|---|
| Source dataset | uspto-grants-1986_10 |
|---|
| ORD ID | ord-515ba7b921994072a46f391815b26e07 |
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| Source note | uspto-grants-1986_10 |
|---|
