Hydrochloric Acid → HCID 178502869, compound

Participants

Reaction Steps

N-(4,6-Dimethoxy-1,3,5-triazin-2-yl) N'-(2-methoxysulfonylbenzenesulfonyl) S-methylisothiourea (4.63 g) was dissolved in dioxane (100 ml), and O-methylhydroxylamine (2.35 g) was added to the solution. The mixture was stirred at room temp. for 4 days. The reaction mixture was poured into ice water, and adjusted to pH 3 with hydrochloric acid. The precipitated crude crystals were collected by filtration, and recrystallized from acetonitrile to give 1.5 g of the desired N-(4,6-dimethoxy-1,3,5-triazin-2-yl) N'-(2-methoxysulfonylbenzenesulfonyl) N"-(methoxy)guanidine represented by the following formula. mp. 148°-150° C. ##STR22## By the same method as in Example 1 or 2, the compounds of the invention shown in Table 1 below were synthesized.

Provenance & Evidence