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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 229112Generated: October 30, 2026

Hydrochloric Acid → 2-(3-{3-[(2-Chloro-3-trifluoromethyl-benzyl)-2,2-diphenylethyl-amino]-propoxy}-phenyl)-butyric acid hydrochloride salt

https://huagongshe.com/reaction/229112

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant2-(3-{3-[(2-Chloro-3-trifluoromethyl-benzyl)-2,2-diphenylethyl-amino]-propoxy}-phenyl)-hexanoic acidHCID 57757131—
SolventDiethyl EtherHCID 3283—
Product2-(3-{3-[(2-Chloro-3-trifluoromethyl-benzyl)-2,2-diphenylethyl-amino]-propoxy}-phenyl)-butyric acid hydrochloride saltHCID 6886424780%

Reaction Steps

To a solution of 2-(3-{3-[(2-Chloro-3-trifluoromethyl-benzyl)-2,2-diphenylethyl-amino]-propoxy}-phenyl)-hexanoic acid in diethyl ether was added HCl in diethyl ether (1.0 M) to precipitate the amine salt. The suspension was filtered and dried to give the title compound as a white solid (30 mg, 80%). MS m/e 609.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07560586B2
Source datasetuspto-grants-2009_07
ORD IDord-da29ed21362444eeaf67140d222d45cd
Source noteuspto-grants-2009_07