HCID 20229697, compound → HCID 20229698, compound

HRID 2291141Notes

Reaction equation

HRID 2291141 reaction equation
[C:1]([C:3]1([CH2:10][CH:11]2[O:15][CH2:14][CH2:13][O:12]2)[CH2:8][CH:7]2[CH2:9][CH:4]1[CH2:5][CH2:6]2)#[N:2].[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[NH2:2][CH2:1][C:3]1([CH2:10][CH:11]2[O:12][CH2:13][CH2:14][O:15]2)[CH2:8][CH:7]2[CH2:9][CH:4]1[CH2:5][CH2:6]2

Participants

3

Reactant 2

HCID 20229697HCID 20229697, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 20229698HCID 20229698, compoundYield 84.6%

Procedure

8 g of 2-cyano-2-(1,3-dioxolan-2-yl)methylbicyclo[2.2.1]heptane are reduced with 4.4 g of lithium aluminum hydride in analogy to Example 1b. 6.9 g of a colorless oil are obtained.

Sources & evidence

ORD record
ord-d72dcb111ec1496a8380cac02fbed18b
Source dataset
uspto-grants-1986_10
Patent number
US04620012

Reaction notes

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