Ammonia → HCID 19856560, compound

HRID 2291231Notes

Reaction equation

HRID 2291231 reaction equation
[CH2:1]([N:3]1[CH:8]=[C:7]([Br:9])[N:6]=[C:5](Br)[C:4]1=[O:11])[CH3:2].[NH3:12]>O1CCOCC1>[CH2:1]([N:3]1[CH:8]=[C:7]([Br:9])[N:6]=[C:5]([NH2:12])[C:4]1=[O:11])[CH3:2]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 19856557HCID 19856557, compound

Product 1

HCID 19856560HCID 19856560, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

A mixture of 4.6 g of 1-ethyl-3,5-dibromopyrazin-2-one, 9.6 ml of dioxane and 6.4 ml of 30% ammonia is stirred at 20°-25° C. for 15 hours. The product is filtered off and washed with alcohol and ether to give 1.3 g of 1-ethyl-3-amino-5-bromo-pyrazin-2-one with a melting point of 227°-230° C.

Workup

  1. filtrationThe product is filtered off
  2. washwashed with alcohol and ether

Sources & evidence

ORD record
ord-04c295e7ac8b490e83a2d2960b49fd04
Source dataset
uspto-grants-1989_01
Patent number
US04795486

Reaction notes

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