Diethyl Ether → HCID 178526021, compound

HRID 2291272Notes

Reaction equation

HRID 2291272 reaction equation
[OH-].[Na+:2].[NH:3]1[C:7]([C:8]2[CH:9]=[C:10]([CH:17]=[CH:18][CH:19]=2)[NH:11][C:12](=[O:16])[C:13]([OH:15])=[O:14])=[N:6][N:5]=[N:4]1.C(OCC)C>CO>[NH:6]1[C:7]([C:8]2[CH:9]=[C:10]([CH:17]=[CH:18][CH:19]=2)[NH:11][C:12](=[O:16])[C:13]([O-:15])=[O:14])=[N:3][N:4]=[N:5]1.[Na+:2].[Na+:2].[NH:6]1[C:7]([C:8]2[CH:9]=[C:10]([CH:17]=[CH:18][CH:19]=2)[NH:11][C:12](=[O:16])[C:13]([O-:15])=[O:14])=[N:3][N:4]=[N:5]1

Participants

5

Reactant 3

HCID 3283Diethyl EtherHCID 14798Sodium HydroxideHCID 178526019HCID 178526019, compound

Product 1

HCID 178526021HCID 178526021, compoundYield 91.1%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Sodium hydroxide (1.72 g; 43 mmol) was dissolved in methanol (100 ml), 3-(1H-tetrazol-5-yl)oxanilic acid (5 g; 21.5 mmol) was added thereto and the mixture was stirred for 1 hour at room temperature. The reaction solution was poured into 300 ml of ethyl ether at room temperature with stirring, the precipitated crystals were filtered off and were dried at 40° C. in vacuo in the presence of phosphorous pentoxide to obtain 5 g (yield 85%) of disodium 3-(1H-tetrazol-5-yl)oxanilate. Decomposition point: not less than 300° C.

Workup

  1. stirringwith stirring
  2. filtrationthe precipitated crystals were filtered off
  3. dry with materialwere dried at 40° C. in vacuo in the presence of phosphorous pentoxide

Sources & evidence

ORD record
ord-5247b4ff142b440cb78804606d6411e1
Source dataset
uspto-grants-1989_01
Patent number
US04795754

Reaction notes

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