Ammonia → HCID 21279873, compound

HRID 2291273Notes

Reaction equation

HRID 2291273 reaction equation
[C:1]([CH2:3][C:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:13]([NH:15][CH2:16][C:17]([O:19]C)=O)=[O:14])[CH:11]=2)[NH:6][CH:5]=1)#[N:2].[NH3:21]>>[NH2:21][C:17](=[O:19])[CH2:16][NH:15][C:13]([C:10]1[CH:11]=[C:12]2[C:7](=[CH:8][CH:9]=1)[NH:6][CH:5]=[C:4]2[CH2:3][C:1]#[N:2])=[O:14]

Participants

3

Reactant 2

HCID 222Ammonia2×HCID 54211094HCID 54211094, compound

Product 1

HCID 21279873HCID 21279873, compound

Procedure

The product of Stage (i) (0.05 g) dissolved in methanolic ammonia (2 ml) was stirred overnight, further 2 ml portions of methanolic ammonia being added after 3.5 h and 5.5 h. The solution was evaporated to dryness and the residual solid triturated with anhydrous ether to present the product as a powder (0.036 g) m.p. 206°-209°.

Workup

  1. customThe solution was evaporated to dryness
  2. customthe residual solid triturated with anhydrous ether

Sources & evidence

ORD record
ord-df8ea2c2aa794172abd3288159fde4ee
Source dataset
uspto-grants-1989_01
Patent number
US04795756

Reaction notes

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