HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylpiperazine → HCID 4914114, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | 5-Amino-1-cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | HCID 13910947 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | HCID 4914114 | HCID 4914114 | — |
Reaction Steps
In the same manner as described in Example 1 (1), a mixture of 5-amino-1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, 1-methylpiperazine, and xylene was refluxed for 3 hours to give 5-amino-1-cyclopropyl-6,8-difluoro-7-(4-methyl-1-piperazinyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, m.p. 254°-255° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04795751 |
| Source dataset | uspto-grants-1989_01 |
| ORD ID | ord-55edbfc86d8a4fd2b79837e9a6173a07 |
| Source note | uspto-grants-1989_01 |