HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2291280Generated: October 30, 2026
5-Amino-1-cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid → HCID 14370087, compound
https://huagongshe.com/reaction/2291280
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 5-Amino-1-cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | HCID 13910947 | — |
| Reactant | HCID 14090597 | HCID 14090597 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 14370087 | HCID 14370087 | — |
Reaction Steps
In the same manner as described in Example 1 (1), a mixture of 5-amino-1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, 1-ethoxycarbonyl-3-methyl-piperazine, and dimethyl sulfoxide was stirred at 150° C. for 2 hours to give 5-amino-1-cyclopropyl-6,8-difluoro-7-(4-ethoxycarbonyl-2-methyl-1-piperazinyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, m.p. 220°-225° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04795751 |
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| Source dataset | uspto-grants-1989_01 |
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| ORD ID | ord-5db303d6748245b89f17dbafaca142f7 |
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| Source note | uspto-grants-1989_01 |
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