HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 4914114, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 13825520 | HCID 13825520 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 4914114 | HCID 4914114 | — |
Reaction Steps
In the same manner as described in Example 13, 1-cyclopropyl-5,6,8-trifluoro-7-(4-methyl-1-piperazinyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid was allowed to react with ammonia in dimethylformamide in a sealed tube to give 5-amino-1-cyclopropyl-6,8-difluoro-7-(4-methyl-1-piperazinyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, m.p. 254°-255° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04795751 |
| Source dataset | uspto-grants-1989_01 |
| ORD ID | ord-77fb75cf9ba24361bc32b863c15d3f13 |
| Source note | uspto-grants-1989_01 |