p-Toluenesulfonic acid → HCID 54572592, compound

Participants

Reaction Steps

To 30 ml of anhydrous diethyl ether solution containing 5 g of ethyl 4-hydroxycinnamate was added 7.1 ml of dihydropyran and 50 mg of p-toluenesulfonic acid were added, the mixture was stirred at room temperature for 2 hours. Then the reaction mixture was neutralized with 1%-sodium hydroxude solution, washed with water, and dried with anhydrous sodium sulfate. The solvent was removed by evaporation to yield 6.8 g of ethyl 4-(2-tetrahydropyranyloxy)cinnamate. Colorless indefinite form crystatls. Melting point: 52°-53° C.

Provenance & Evidence