Ammonia → HCID 70043308, compound

HRID 2291355Notes

Reaction equation

HRID 2291355 reaction equation
[C:1]([O:7][CH2:8][CH:9]=[CH:10][C:11]1[CH:16]=[CH:15][C:14]([O:17][CH2:18][CH2:19][O:20][CH2:21][CH3:22])=[CH:13][CH:12]=1)(=[O:6])[CH2:2][C:3]([CH3:5])=O.[NH3:23].O>C1(C)C=CC=CC=1>[NH2:23]/[C:3](/[CH3:5])=[CH:2]\[C:1]([O:7][CH2:8][CH:9]=[CH:10][C:11]1[CH:16]=[CH:15][C:14]([O:17][CH2:18][CH2:19][O:20][CH2:21][CH3:22])=[CH:13][CH:12]=1)=[O:6]

Participants

5

Reactant 3

HCID 222AmmoniaHCID 962WaterHCID 542124814-[(1-Ethoxy)ethoxy]cinnamyl acetoacetate

Product 1

HCID 70043308HCID 70043308, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

10 Grams of 4-[(1-ethoxy)ethoxy]cinnamyl acetoactate was dissolved in 20 ml of toluene, then 2 g of ammonia gas was passed through this solution at about 80° C. with stirring condition. The water formed during the reaction was removed by azeotropic distillation with toluene. 2 Hours after the azeotropic distillation, the toluene was removed by distillation under reduced pressure to yield 10 g of 4-[(1-ethoxy)ethoxy]cinnamyl 3-aminocrotonate as in the form of an oily substance.

Workup

  1. customwas passed through this solution at about 80° C.
  2. customwas removed by azeotropic distillation with toluene
  3. distillation2 Hours after the azeotropic distillation
  4. customthe toluene was removed by distillation under reduced pressure

Sources & evidence

ORD record
ord-64e752436861484187366bc64f4cb596
Source dataset
uspto-grants-1989_01
Patent number
US04795814

Reaction notes

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