Sodium Hydroxide → Acifluorfen sodium

HRID 2291413Notes

Reaction equation

HRID 2291413 reaction equation
[Cl:1][C:2]1[CH:20]=[C:19]([C:21]([F:24])([F:23])[F:22])[CH:18]=[CH:17][C:3]=1[O:4][C:5]1[CH:6]=[CH:7][C:8]([N+:14]([O-:16])=[O:15])=[C:9]([CH:13]=1)[C:10]([OH:12])=[O:11].[OH-].[Na+:26]>CO>[Cl:1][C:2]1[CH:20]=[C:19]([C:21]([F:22])([F:23])[F:24])[CH:18]=[CH:17][C:3]=1[O:4][C:5]1[CH:6]=[CH:7][C:8]([N+:14]([O-:16])=[O:15])=[C:9]([CH:13]=1)[C:10]([O-:12])=[O:11].[Na+:26]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 44073Acifluorfen

Product 1

HCID 44072Acifluorfen sodiumYield 105.4%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

5-(2-Chloro-4-trifluoromethylphenoxy)-2-nitrobenzoic acid (1.7 g, 0.0047 mole) is dissolved in methanol (25 ml) and sodium hydroxide (4.7 ml of 1N NaOH in methanol, 0.0047 mole) is added rapidly. The solvent is then removed in vacuo to give 1.9 g of product that decomposes at 217° C.

Workup

  1. customThe solvent is then removed in vacuo

Sources & evidence

ORD record
ord-4ecc83dd880344eb9c908705cd926f68
Source dataset
uspto-grants-1989_01
Patent number
US04795825

Reaction notes

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