Pyridine → HCID 15595583, compound

Participants

Reaction Steps

12.8 g (50 millimoles) of 3,7-dichloroquinoline- 8-carboxylic hydrazide (compound No. 1) were suspended in 100 ml of dimethoxyethane, 7.9 g (100 millimoles) of pyridine were added and phosgene was then passed in over a period of 4 hours at 25° C. Excess phosgene and the solvent were removed, the residue was stirred into water and the mixture was filtered under suction to give 8.7 g (62%) of a product of melting point of 87° C. (compound No. 33).

Provenance & Evidence