Pyridinium chloride → HCID 14350669, compound

Participants

Reaction Steps

A mixture of 5,6-dichloro-7-methoxy-9a-propyl-1,2,9,9a-tetrahydro-3H-fluoren-3,9-dione (2.67 g) and pyridine hydrochloride (35 g) was heated at 175°-180° C. in an inert atmosphere for 3/4 hour, poured into ice water and extracted with a mixture of ether and tetrahydrofuran. The organic extracts were washed with water, dried over MgSO4 and evaporated in vacuo to give 5,6-dichloro-7-hydroxy-9a-propyl-1,2,9,9a-tetrahydro-3H-fluoren-3,9-dione which was used in Step E without further purification.

Provenance & Evidence